The draw for the Carabao Cup semi-finals took place on Wednesday night.
Southampton, who knocked out Premier League champions Manchester City, will face Newcastle United.
Manchester United, the favorite to win the competition, faces Nottingham Forest.
The home and away matches will take place in the week of January 23 and January 30, respectively.
The final will take place on February 26 at Wimbledon.
Carabao Cup semi-final draw:
Southampton / Newcastle United
Nottingham Forest x Manchester United
Confirmation of the Carabao Cup semi-final draw [Full fixtures]